What is EB?

Epidermolysis Bullosa is a painful, life threatening disease of the skin. Sammy has the form called Recessive Dystrophic. In his case the bottom layer of his skin does not adhere properly to the other layers because the collagen 7 protein involved in this function is either missing or mis-shapen.
Because of this genetic defect even slight friction can cause several layers of skin to rip away creating horrific, painful wounds. Normal daily activities can cause blistering or tearing of the skin. Currently there is no cure for EB, only wound management as treatment. Despite the challenges Sam faces with EB, he displays amazing strength every day and inspires those around him.

Friday, October 26, 2012

EB Skin Lesson

This Chart shows the layers of skin and the various locations that the skin will detach due to the inability of the anchoring filaments to hook the layers together.

The main forms of EB are:
EB Simplex, Junctional EB, and Dystrophic EB(
Dominant or Recessive).
EB Simplex occurs in the outer layer of skin;
Junctional EB and Dystrophic EB occur in the basement membrane zone.

This information was borrowed from a Dept of Health Pamphlet on EB.

No comments:

Post a Comment